- Title
- Diabetes distress and depression are independently associated with gastrointestinal symptoms in type 2 diabetes in Bangladesh
- Creator
- Kamruzzaman, M.; Horowitz, M.; Polonsky, W. H.; Talley, N. J.; Borg, M. A.; Rayner, C. K.; Jones, K. L.; Marathe, C. S.
- Relation
- Diabetic Medicine Vol. 41, Issue 11, no. e15379
- Publisher Link
- http://dx.doi.org/10.1111/dme.15379
- Publisher
- Wiley-Blackwell
- Resource Type
- journal article
- Date
- 2024
- Description
- Background and Aims: Gastrointestinal (GI) symptoms, common in type 2 diabetes (T2D), are typically bothersome, socially embarrassing, and impact negatively on quality of life. They may also contribute to diabetes distress (DD), but this has never been formally evaluated. We aimed to investigate the relationships between GI symptoms, DD and depressive symptoms in a large cohort of individuals with T2D in Bangladesh. Materials and Methods: 1406 unselected T2D individuals (female 58.8%; mean age 51.0 ± 12.5 years) from four diabetes clinics in Bangladesh completed validated questionnaires evaluating GI symptoms (PAGI-SYM), DD (DDS-17) and depressive symptoms (PHQ-9). Results: 31.1% of participants reported GI symptoms (36.2% females, 23.7% males), while 51.1% had elevated DD and 37.8% depressive symptoms. GI symptoms exhibited independent relationships with both DD and depressive symptoms, and their likelihood was higher among those with DD (OR: 3.6 [2.2–5.6] and with depressive symptoms (OR: 5.9 [3.5–9.9]). Conclusions: GI symptoms are independently associated with both DD and depressive symptoms in people with T2D in Bangladesh.
- Subject
- Bangladesh; depressive symptoms; diabetes distress; gastrointestinal symptoms; type 2 diabetes; SDG 3; Sustainable Development Goal
- Identifier
- http://hdl.handle.net/1959.13/1513961
- Identifier
- uon:56792
- Identifier
- ISSN:0742-3071
- Rights
- © 2024 The Author(s). Diabetic Medicine published by John Wiley & Sons Ltd on behalf of Diabetes UK. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
- Language
- eng
- Full Text
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